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18F-PSMA 1007 Brain PET/CT Imaging in Glioma Recurrence

Marafi, Fahad MD, KBNM*; Sasikumar, Arun MD; Fathallah, Wael FRCR; Esmail, Abdulredh MD, KBNM*

doi: 10.1097/RLU.0000000000002668
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A 64-year-old man with a known case of right parietal lobe glioblastoma multiforme operated on in August 2018 was referred for 18F-FDG PET/CT with a clinical suspicion of recurrence. He underwent 18F-FDG and 18F-PSMA 1007 scans. Both the scans showed intense tracer uptake in right parietal lobe lesion, which concurred with MRI findings of recurrent disease and was later proven on histopathologic examination as recurrence. Our case highlights the feasibility of 18F-PSMA 1007 PET/CT imaging of suspected glioblastoma recurrence. Considering its similarity to PSMA-617, it may be used as a surrogate imaging tracer for potential theranostic application using alpha or beta emitters.

From the *Jaber Alahmad Centre for Molecular Imaging, Shuwaikh, Kuwait;

St Gregorios International Cancer Care Centre, Parumala, Kerala, India; and

Kuwait Cancer Control Centre, Shuwaikh, Kuwait.

Received for publication May 1, 2019; revision accepted May 2, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Arun Sasikumar, MD, Department of Nuclear Medicine, St Gregorios International Cancer Care Centre, Parumala, Pathanmthitta, Kerala, India. E-mail:

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