Interesting ImagesSuperiority of 68Ga-FAPI-04 in Delineation of Soft Tissue and Liver Metastases in Chromophobe Renal Cell Carcinoma for RestagingXie, Fei MD; Fu, Lilan MD; Zhou, Wenlan MD, PhD Author Information From the Department of NanFang PET Center, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong Province, China. Received for publication April 20, 2022; revision accepted July 4, 2022. Conflicts of interest and sources of funding: none declared. F.X. and L.F. contributed equally to this work and shared joint first authorship. Correspondence to: Wenlan Zhou, MD, PhD, Nanfang PET Center, Nanfang Hospital, Southern Medical University, No. 1838, North Guangzhou Avenue, Guangzhou 510515, China. E-mail: [email protected]. Clinical Nuclear Medicine: December 2022 - Volume 47 - Issue 12 - p e758-e759 doi: 10.1097/RLU.0000000000004374 Buy Metrics Abstract Chromophobe renal cell carcinoma (RCC) is a rare tumor. We described findings of 18F-FDG PET/CT and 68Ga-FAPI-04 PET/CT of metastatic chromophobe RCC in a 56-year-old woman. 68Ga-FAPI-04 PET/CT demonstrated that the metastatic lesions in the liver, left posterior abdominal wall, and the left waist had intense uptake of 68Ga-FAPI-04, which was higher than that of 18F-FDG on 18F-FDG PET/CT. 68Ga-FAPI-04 PET/CT also delineated the metastatic lesions more clearly than 18F-FDG PET/CT. This case highlights 68Ga-FAPI-04 PET/CT may be promising in restaging of chromophobe RCC. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.