Interesting ImagesSerous Cystadenoma of the Pancreas Showing Increased Uptake on 68Ga-FAPI PET/CTXu, Weizhi MD; Zhao, Long MD; Meng, Tinghua MD; Shang, Qihang MD; Chen, Haojun MD, PhD Author Information From the Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Center, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China. Received for publication May 19, 2022; revision accepted June 15, 2022. Conflicts of interest and sources of funding: The authors declare that they have no conflicts of interest. This report was sponsored by the National Natural Science Foundation of China (grand number 82071961). W.X. and L.Z. contributed equally to this work. Correspondence to: Haojun Chen, MD, PhD, Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Center, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, 55 Zhenhai Rd, Xiamen 361003, China. E-mail: [email protected]. Clinical Nuclear Medicine: December 2022 - Volume 47 - Issue 12 - p 1095-1098 doi: 10.1097/RLU.0000000000004348 Buy Metrics Abstract Serous cystadenoma of the pancreas is a type of pancreatic cystic neoplasm frequently found in clinical practice. Serous cystadenoma of the pancreas can have a varied morphological presentation on imaging examinations. Therefore, it is sometimes very challenging to differentiate serous cystadenoma of the pancreas from pancreatic malignancy. In this study, we present a case of serous cystadenoma of the pancreas showing focally elevated radiotracer uptake on 68Ga-FAPI PET/CT. Considering potential future clinical use of 68Ga-FAPI PET/CT in malignancy, awareness of the false-positive findings is important for the differential diagnosis and management of these lesions. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.