Interesting ImagesComparison of 18F-MFBG and 68Ga-DOTATATE PET/CT in the Imaging of Metastatic Paraganglioma and PheochromocytomaDeng, Maoxue MD∗,†,‡; Shu, Qiaoqiao MD∗,†,‡; Hu, Mei MD§; Chen, Yue MD∗,†,‡; Cai, Liang PhD∗,†,‡ Author Information From the ∗Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University †Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province ‡Institute of Nuclear Medicine §School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, China. Received for publication March 14, 2022; revision accepted May 12, 2022. Conflicts of interest and sources of funding: none declared. Correspondence to: Liang Cai, PhD, Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping St, Luzhou, Sichuan, China 646000. E-mail: [email protected]. Clinical Nuclear Medicine: December 2022 - Volume 47 - Issue 12 - p e735-e737 doi: 10.1097/RLU.0000000000004314 Buy Metrics Abstract Two men with metastatic paraganglioma/pheochromocytoma underwent PET/CT examination in our hospital to understand the treatment effect and progression of the disease. Both patients had previously been treated with 131I-MIBG, and at this evaluation, both of them underwent 68Ga-DOTATATE and 18F-MFBG PET/CT. The 68Ga-DOTATATE PET/CT showed more metastases in the images of these 2 patients. This case highlighted that 68Ga-DOTATATE PET/CT is superior to 18F-MFBG PET/CT in detecting metastases from paraganglioma and pheochromocytoma in these 2 patients. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.