Interesting Images18F-FDG and 18F-Fluciclovine Uptake in Poorly Differentiated Lung Adenocarcinoma in the Setting of Biochemically Recurrent Prostatic AdenocarcinomaTrak, Joseph MD, MBiotech∗; Hasanovic, Adnan MD†; Gavane, Somali MD∗ Author Information From the ∗Division of Nuclear Medicine, Department of Radiology †Department of Pathology, Mount Sinai Hospital, New York, NY. Received for publication April 29, 2022; revision accepted August 4, 2022. Conflicts of interest and sources of funding: none declared. Correspondence to: Somali Gavane, MD, Division of Nuclear Medicine, Department of Radiology, Mount Sinai Hospital, 1190 Fifth Ave, MC Level, New York, NY 10029. E-mail: [email protected]. Clinical Nuclear Medicine: December 2022 - Volume 47 - Issue 12 - p 1077-1078 doi: 10.1097/RLU.0000000000004387 Buy Metrics Abstract A 64-year-old man with a history of Gleason 7 (3 + 4) pT2cN0 prostatic adenocarcinoma status post prostatectomy underwent a fluciclovine PET/CT that showed a tracer-avid right upper lobe spiculated solitary pulmonary nodule. Follow-up FDG PET/CT showed a hypermetabolic right upper lobe spiculated solitary pulmonary nodule. Fine-needle aspiration was consistent with primary lung adenocarcinoma. Subsequently, right upper lobectomy was performed, and poorly differentiated lung adenocarcinoma was confirmed. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.