Interesting ImagesPulmonary Artery Sarcoma With Low 18F-FDG UptakeRosales Castillo, Juan José MD∗; García, Laura MD†; Bastidas, Juan Fernando MD∗; Bronte, Ángela MD∗; García-Velloso, María José MD, PhD∗Author Information From the Departments of ∗Nuclear Medicine †Pathology, Clínica Universidad de Navarra, Pamplona, Spain. Received for publication June 15, 2020; revision accepted September 20, 2020. Conflicts of interest and sources of funding: none declared. Correspondence to: Juan José Rosales Castillo, MD, Department of Nuclear Medicine, Clínica Universidad de Navarra, Avda Pío XII 36, Pamplona, Spain. E-mail: [email protected]. Clinical Nuclear Medicine: February 2021 - Volume 46 - Issue 2 - p e127-e128 doi: 10.1097/RLU.0000000000003376 Buy Metrics Abstract A 75-year-old man presented with dyspnea for more than 2 months, with blood test showing low platelet count and cardiac ultrasound showing severe pulmonary hypertension (>54 mm Hg). A CT pulmonary angiogram showed a filling defect in the pulmonary trunk, right and left pulmonary arteries, raising the possibilities of pulmonary embolism or artery sarcoma. FDG PET/CT was performed for further evaluation and showed low uptake in the pulmonary wall, which supported the diagnosis of pulmonary embolism. Patient was treated with anticoagulants with no changes on repeated CT pulmonary angiogram. Patient underwent surgery, and histopatological examination revealed a pulmonary artery sarcoma. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.