Interesting ImagesIncidental Findings of a Vestibular Schwannoma on 18F-Choline PET/CTAmrane, Karim MD∗; Le Pennec, Romain MSc∗; Tissot, Valentin MD†; Schick, Ulrike MD, PhD‡; Abgral, Ronan MD, PhD∗,§Author Information From the Departments of ∗Nuclear Medicine †Radiology ‡Radiotherapy, University Hospital of Brest §EA 3878 GETBO, IFR 148, Bretagne Loire University, Brest, France. Received for publication March 23, 2020; revision accepted October 12, 2020. Conflicts of interest and sources of funding: none declared. Correspondence to: Ronan Abgral, MD, PhD, Department of Nuclear Medicine, University Hospital of Brest, 2 Avenue Foch, 29609 Brest Cedex, France. E-mail: [email protected]. Clinical Nuclear Medicine: February 2021 - Volume 46 - Issue 2 - p e75-e77 doi: 10.1097/RLU.0000000000003427 Buy Metrics Abstract We report an increased uptake of 18F-choline in the right cerebellopontine angle area in a 73-year-old man with biochemical failure prostate cancer after radical prostatectomy, potentially suggestive of bone metastasis in the base of the skull. A brain MRI was also performed showing an intense gadolinium enhancement focus in the same area, concordant with a right vestibular schwannoma, subsequently histologically proven. This case underlines that schwannoma is a diagnostic pitfall in 18F-choline PET/CT, suggesting this radiolabeled tracer as a promising tool for brain tumors characterization due to its higher signal-to-background ratio than 18F-FDG. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.