Interesting ImagesFDG-Avid Pulmonary Nodules and Tracheobronchial Mural Inflammation in IgG4-Related DiseaseNamireddy, Meera K. MD∗; Consul, Nikita MD∗; Sher, Andrew C. MD∗,†Author Information From the ∗Department of Radiology, Baylor College of Medicine †Department of Radiology, Texas Children’s Hospital, Houston, TX. Received for publication June 14, 2020; revision accepted September 12, 2020. Conflicts of interest and sources of funding: none declared. Authors’ contributions: M.K.N., N.C., and A.C.S. reviewed the patient case and contributed to the final draft of the manuscript; M.K.N. and N.C. performed the literature search; M.K.N. wrote the initial draft of the manuscript; and N.C. and A.C.S. reviewed and edited the manuscript. Correspondence to: Meera K. Namireddy, MD, Department of Radiology, Baylor College of Medicine, 1 Baylor Plaza, BCM-360, Houston, TX 77030. E-mail: [email protected]. Clinical Nuclear Medicine: February 2021 - Volume 46 - Issue 2 - p e125-e126 doi: 10.1097/RLU.0000000000003358 Buy Metrics Abstract We report the case of a 9-year-old girl who presented with acute fevers, cough, and epistaxis with nasal swelling, and found to have a nasal mass. On 18F-FDG PET/CT, she was found to have marked nodal and pulmonary parenchymal disease with diffuse and symmetrical mural FDG uptake within the trachea and bronchial tree. The differential diagnosis was broad, and she was diagnosed with IgG4-RD (IgG4-related disease) and improved on appropriate treatment. To our knowledge, there are only 2 other pediatric cases of IgG4-related pulmonary disease in the literature, and our case serves as a unique constellation of intrapulmonary IgG4-RD imaging findings. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.