Interesting ImagesPara-aortal Ganglion Mimicking a Lymph Node Metastases on 68Ga-PSMA PET/CTSchweighofer Zwink, Gregor MD∗; Rendl, Gundula MD, PhD∗; Schmeller, Nikolaus MD†; Pirich, Christian MD∗Author Information From the ∗Clinic for Nuclear Medicine and Endocrinology, Paracelsus Medical University †Private Clinic Wehrle-Diakonissen, Salzburg, Austria. Received for publication March 25, 2020; revision accepted July 1, 2020. Conflicts of interest and sources of funding: none declared. Correspondence to: Gregor Schweighofer Zwink, MD, Clinic for Nuclear Medicine and Endocrinology, Paracelsus Medical University, Muellner Hauptstraße 48, 5020 Salzburg, Austria. E-mail: firstname.lastname@example.org. Clinical Nuclear Medicine: November 2020 - Volume 45 - Issue 11 - p 883-885 doi: 10.1097/RLU.0000000000003247 Buy Metrics Abstract PSMA-based nuclear medicine imaging impacts increasingly the clinical decision process in prostate cancer patients. A well-known PSMA pitfall is uptake into autonomic ganglia. The intensity of uptake, the shape, and the exact location of the correlating structure in CT are supposed to aid discriminating between ganglia and lymph node metastases. In this patient, we found intense uptake in a nodular shaped para-aortal soft tissue lesion suspicious of a lymph node metastases at staging as well as restaging. After secondary resection, the lesion was histologically proven an autonomic ganglion with intense PSMA expression. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.