Interesting ImagesMalignant Peripheral Nerve Sheath Tumor Arising From Transplanted Kidney Assessed by 18F-FDG PET/CTFeng, Hongyan MD, PhD; Tu, Ning MD, PhD; Bu, Lihong MD, PhDAuthor Information From the PET-CT/MRI Center and Molecular Imaging Center, Renmin Hospital of Wuhan University, Wuhan, Hubei, China. Received for publication May 19, 2020; revision accepted July 23, 2020. Conflicts of interest and sources of funding: This work was partially supported by the National Natural Science Foundation of China (grant 81701735 to H.F. and grant 81871419 to L.B.), and Seed project in Sino Foreign Joint Research Platform of Wuhan University (2309-413100006 to L.B.). None declared to all other authors. Correspondence to: Lihong Bu, MD, PhD, PET-CT/MRI Center and Molecular Imaging Center, Renmin Hospital of Wuhan University, Wuhan, Hubei, China 430060. E-mail: [email protected]. Clinical Nuclear Medicine: November 2020 - Volume 45 - Issue 11 - p 905-907 doi: 10.1097/RLU.0000000000003273 Buy Metrics Abstract Malignant peripheral nerve sheath tumor (MPNST) originates from Schwann cells or pluripotent perineural cells, which is an extremely rare tumor that occurs in the kidney. We report a case of MPNST in transplanted kidney that was diagnosed in a 32-year-old man with a history of kidney transplantation. Contrast-enhanced MRI and 18F-FDG PET/CT features of MPNST are described, which can accurately discriminate MPNST from infection and benign tumors. These features could potentially provide valuable information to distinguish it from other renal malignancies. 18F-FDG PET/CT may be a useful tool for the primary diagnosis and the initial staging of MPNST. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.