Interesting ImagesIntense Increased 18F-FDG Uptake of Masticator Muscles After Cocaine UseMeneret, Pierre MD; Palard-Novello, Xavier MD, PhD; Cuvilliers, Cécile MD; Girard, Antoine MD; Pontoizeau, Clémence MDAuthor Information From the Department of Nuclear Medicine, Eugene Marquis Center, Rennes, France. Received for publication June 10, 2020; revision accepted August 2, 2020. Conflicts of interest and sources of funding: none declared. Correspondence to: Clemence Pontoizeau, MD, Department of Nuclear Medicine, Eugene Marquis Center, Avenue de la Bataille Flandres-Dunkerque, 35000 Rennes, France. E-mail: [email protected]. Clinical Nuclear Medicine: November 2020 - Volume 45 - Issue 11 - p 919-920 doi: 10.1097/RLU.0000000000003288 Buy Metrics Abstract 18F-FDG is the most widely used PET tracer worldwide. Before the examination, recommendations are given to patients to avoid muscular activities, with the goal to limit 18F-FDG uptake in muscles. Here, we report the case of a 36-year-old man with Hodgkin disease referred to our department to perform an 18F-FDG PET/CT for immunotherapy assessment. The PET images showed a homogeneous, symmetric, and very intense uptake of the masticatory muscles. The medical examination exhibited a trismus, and the patient revealed to have been using cocaine 15 minutes before injection of 18F-FDG. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.