Interesting ImagesEven Small Pleural Effusion Could Be Potential Pitfall on Posttherapeutic 131I ScintigraphyPeng, Dong MD∗,†; Shao, Fuqiang MD‡Author Information From the ∗Department of Nuclear Medicine, Chongqing University Three Gorges Hospital †Department of Nuclear Medicine, Chongqing Three Gorges Central Hospital, Chongqing ‡Department of Nuclear Medicine, Zigong First People’s Hospital, Zigong, Sichuan, People’s Republic of China. Received for publication June 29, 2020; revision accepted July 22, 2020. Conflicts of interest and sources of funding: This work is supported by the Open Program of Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province (no. HYX19026). None declared to all authors. Correspondence to: Fuqiang Shao, MD, Department of Nuclear Medicine, Zigong First People’s Hospital, No. 42, Shangyihao 1st Branch, Ziliujing District, Zigong, Sichuan Province 643000, People’s Republic of China. E-mail: email@example.com. Clinical Nuclear Medicine: November 2020 - Volume 45 - Issue 11 - p 925-926 doi: 10.1097/RLU.0000000000003267 Buy Metrics Abstract Pleural and pericardiac effusion could have radioiodine accumulation and be potential pitfall on posttherapeutic 131I whole-body scintigraphy. However, the volume of the effusion was relatively massive in the previous publications. We report a case of pleural effusion with a very small volume also had radioiodine uptake in a 37-year-old man. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.