Interesting ImagesA Case of Primary Sacral Lymphoma Evaluated by 18F-FDG PET/CTXu, Tingting MD; Fu, Wenhui MD; Zhang, Xinyi MD; Chen, Yue MDAuthor Information From the Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University; and Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, Luzhou, Sichuan, People’s Republic of China. Received for publication March 26, 2020; revision accepted May 24, 2020. Conflicts of interest and sources of funding: none declared. T.X. and W.F. contributed equally to this work and shared joint first authorship. Correspondence to: Yue Chen, MD, Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University, Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, No. 25 TaiPing St, Jiangyang District, Luzhou, Sichuan 646000, People’s Republic of China. E-mail: email@example.com. Clinical Nuclear Medicine: November 2020 - Volume 45 - Issue 11 - p 888-889 doi: 10.1097/RLU.0000000000003195 Buy Metrics Abstract Primary sacral lymphoma is an unusual bone malignant tumor that poses a diagnostic challenge. Herein, we report a rare case of primary sacral lymphoma, which was initially assessed as suspicious bone metastasis. The subsequent histology and immunohistochemistry of the sacral biopsy confirmed the diagnosis of diffuse large B-cell lymphoma. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.