Interesting ImagesA Case of Localized Malignant Peritoneal Mesothelioma Evaluated by 18F-FDG PET/CTXu, Tingting MD∗,†; Hu, Jiajia MD‡; Zhang, Xinyi MD∗,†; Cao, Jianpeng MD∗,†; Chen, Yue MD∗,†Author Information From the ∗Department of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University †Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province ‡Department of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China. Received for publication March 29, 2020; revision accepted May 3, 2020. Conflicts of interest and sources of funding: none declared. Correspondence to: Yue Chen, MD, Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province, No. 25 TaiPing St, Jiangyang District, Luzhou, Sichuan 646000, China. E-mail: firstname.lastname@example.org. Clinical Nuclear Medicine: November 2020 - Volume 45 - Issue 11 - p 890-891 doi: 10.1097/RLU.0000000000003158 Buy Metrics Abstract Localized malignant mesothelioma is rare. The prognosis is generally more favorable for this condition than for diffuse malignant mesothelioma. An elderly woman recently complained of abdominal pain, fever, and weight loss. She had no history of asbestos exposure. Her serum CEA level was elevated. Plain CT revealed a mass under the left diaphragm, with liquefaction and necrosis. A contrast-enhanced scan showed circular enhancement of the mass. A subsequent biopsy of the mass revealed a poorly differentiated carcinoma. PET/CT showed a significant FDG-avid subphrenic mass without any indications of metastasis. Postoperative pathological and immunohistochemical examination confirmed a case of malignant mesothelioma. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.