Interesting ImagesSolitary Hard Palate Langerhans Cell Histiocytosis Demonstrated on PET/CT Scan in an AdultChen, Haotian MD; Fan, Qiuping MD; Su, Minggang MDAuthor Information From the Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, China. Received for publication April 12, 2020; revision accepted June 26, 2020. Haotian Chen and Qiuping Fan contributed equally to this work. Conflicts of interest and sources of funding: This study was supported by the Key Projects of the Ministry of Science and Technology (grant 2017YFC0113304). None declared to all authors. Correspondence to: Minggang Su, MD, Department of Nuclear Medicine, West China Hospital, Sichuan University, #37 Guo Xue Lane, Chengdu 610041, China. E-mail: email@example.com. Clinical Nuclear Medicine: October 2020 - Volume 45 - Issue 10 - p 811-812 doi: 10.1097/RLU.0000000000003248 Buy Metrics Abstract Langerhans cell histiocytosis (LCH) is rare in adults. Oral and maxillofacial LCH commonly affects the bones of the skull and jaws. Here we report a case of a 57-year-old man with a painless oral mass evaluated by 18F-FDG PET/CT. PET/CT showed a solitary 18F-FDG-avid tumor in his left hard palate. LCH was confirmed after surgery. This case reminds us that LCH should be considered in an adult with hypermetabolic hard palate lesion on 18F-FDG PET/CT. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.