Interesting ImagesBlood-Pool SPECT/CT in Chronic Ankle TendinopathyCuvilliers, Cécile MD∗; Icard, Nicolas MD†; Meneret, Pierre MD∗; Palard-Novello, Xavier MD, PhD∗; Girard, Antoine MD∗Author Information From the ∗Department of Nuclear Medicine, Eugène Marquis Center, Rennes †Centre d’Explorations Isotopiques, Saint-Grégoire Private Hospital, Saint-Grégoire, France. Received for publication February 18, 2020; revision accepted April 10, 2020. Conflicts of interest and sources of funding: none declared. Correspondence to: Antoine Girard, MD, Department of Nuclear Medicine, Eugène Marquis Center, Avenue de la Bataille Flandres-Dunkerque, 35000 Rennes, France. E-mail: email@example.com. Clinical Nuclear Medicine: October 2020 - Volume 45 - Issue 10 - p e457-e458 doi: 10.1097/RLU.0000000000003119 Buy Metrics Abstract We report 2 cases where blood-pool SPECT/CT had a high added value compared with standard 3-phase bone scintigraphy with only delayed SPECT/CT for the etiological diagnosis of painful ankles. Two men, aged 48 and 62 years, were referred for suspicions of medial and lateral malleoli stress fractures, respectively. Although standard planar blood-pool imaging and delayed SPECT/CT were inconclusive, blood-pool SPECT/CT showed markedly increased uptake along posterior tibial tendon and peroneal tendon, respectively, leading to diagnose tendonitises. These cases illustrate that blood-pool SPECT/CT can extend the diagnostic yield of bone scintigraphy to extraosseous origin, particularly in chronic lower extremities pain. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.