Interesting ImagesUrinary Reflux Into the Prostate Gland and Seminal Vesicles A Potential Pitfall in 18F-FDG and 68Ga-PSMA PET/CTHekimsoy, Turkay MD∗; Gorur, Gozde Daglioz MD∗; Isgoren, Serkan MD∗; Uslu, Hande MD†; Demir, Hakan MD∗Author Information From the Departments of ∗Nuclear Medicine †Radiology, Kocaeli University School of Medicine, Kocaeli, Turkey. Received for publication October 24, 2019; revision accepted March 12, 2020. Conflicts of interest and sources of funding: none declared. Correspondence to: Turkay Hekimsoy, MD, Department of Nuclear Medicine, Kocaeli University School of Medicine, Umuttepe, 41380, Kocaeli, Turkey. E-mail: email@example.com. Clinical Nuclear Medicine: July 2020 - Volume 45 - Issue 7 - p 536-537 doi: 10.1097/RLU.0000000000003069 Buy Metrics Abstract A 64-year-old man with lung cancer underwent 18F-FDG PET/CT for restaging, which demonstrated intense 18F-FDG uptake in the right lobe of prostate gland and seminal vesicles, indicating a potential prostate cancer. In 68Ga-PSMA PET/CT, intense uptake in the right lobe of prostate gland and seminal vesicles was also observed but decreased in postmictional delayed images. Magnetic resonance imaging showed high signal intensity of urine in the same areas of uptakes. 18F-FDG and 68Ga-PSMA PET/CT findings in the prostate gland and seminal vesicles were considered to be a result of urinary reflux possibly because of the patient’s previous transurethral resection. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.