Interesting ImagesSpectrum of Frontotemporal Lobar Degeneration on 18F-FDG PET/CT ScanSeniaray, Nikhil DRM, DNB∗; Verma, Ritu DNB∗; Ranjan, Rajeev MD, DNB†; Belho, Ethel DRM∗; Gupta, Vanshika DNB∗; Mahajan, Harsh MD∗Author Information From the ∗Department of Nuclear Medicine and PET/CT, Mahajan Imaging Centre †Department of Neurology, Sir Ganga Ram Hospital, Old Rajinder Nagar, New Delhi, India. Received for publication September 13, 2019; revision accepted March 19, 2020. Conflicts of interest and sources of funding: none declared. Correspondence to: Nikhil Seniaray, DRM, DNB, Department of Nuclear Medicine and PET/CT, Mahajan Imaging Centre, Sir Ganga Ram Hospital, Old Rajinder Nagar, New Delhi 110060, India. E-mail: firstname.lastname@example.org. Clinical Nuclear Medicine: July 2020 - Volume 45 - Issue 7 - p e311-e316 doi: 10.1097/RLU.0000000000003088 Buy Metrics Abstract FTLD (Frontotemporal lobar degeneration) is a clinically and pathologically heterogeneous group of degenerative disorders, characterized by predominantly asymmetric degeneration of frontal and temporal lobes with selective neuronal loss and gliosis. The disease presents with variable degrees of impairment in behavior, language, executive control, and motor symptoms with progressive loss of cognition. On the basis of presenting clinical symptoms, FTLD is further divided into behavioral variant, nonfluent/agrammatic variant primary progressive aphasia (PPA), semantic variant PPA, logopenic variant PPA, progressive supranuclear palsy, and corticobasal ganglionic degeneration. Here we illustrate the utility of FDG PET with statistical parametric analysis for evaluation of these patients. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.