Interesting ImagesPost Contusion Breast Hematoma Mimicking Malignancy on FDG PET/CTLevin, Daniel MD∗; Lantsberg, Sophie MD∗; Giladi, Maia Rosenthal MD†; Kazap, Dina Ezroh MD∗; Hod, Nir MHA, MD∗Author Information From the ∗Institute of Nuclear Medicine and Molecular Imaging The †Breast Imaging Unit of the Radiology Division, Soroka University Medical Center, Beer-Sheva, Israel (Affiliated to Ben Gurion University of the Negev, Faculty of Health Sciences). Received for publication December 9, 2019; revision accepted March 6, 2020. Conflicts of interest and sources of funding: none declared. Correspondence to: Nir Hod, MHA, MD, Institute of Nuclear Medicine and Molecular Imaging, Soroka University Medical Center, Rager Boulevard, PO Box 151, Beer-Sheva 84101, Israel. E-mail: email@example.com. Clinical Nuclear Medicine: July 2020 - Volume 45 - Issue 7 - p 552-554 doi: 10.1097/RLU.0000000000003050 Buy Metrics Abstract A 32-year-old woman was treated for breast carcinoma. Posttreatment FDG PET/CT scan revealed complete response, but in the contralateral breast, unexpected incidental intense FDG uptake was seen with a differential diagnosis of both malignant and benign causes. Medical history revealed recent breast contusion. The lesion was further evaluated by mammogram and ultrasound, which were compatible with deep breast bruise. Histopathology showed no malignancy. Subsequent FDG PET/CT study showed breast uptake normalization. This case shows that postcontusion breast hematoma can cause a potential pitfall mimicking breast malignancy on FDG PET/CT. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.