Interesting ImagesPelvic Leiomyosarcoma With Splenic Metastasis and Response Assessment by 18F-FDG PET/CTYadav, Divya MD∗; Kumar, Rakesh MD∗; Rastogi, Sameer DM, MD†; Shamim, Shamim Ahmed MD∗Author Information From the Departments of ∗Nuclear Medicine †Medical Oncology, IRCH, All India Institute of Medical Sciences, New Delhi, India. Received for publication November 28, 2019; revision accepted March 6, 2020. Conflicts of interest and sources of funding: none declared. Correspondence to: Shamim Ahmed Shamim, MD, Department of Nuclear Medicine, All India Institute of Medical Sciences, Rajkumari Amrit Kaur OPD, New Delhi, India. E-mail: firstname.lastname@example.org. Clinical Nuclear Medicine: July 2020 - Volume 45 - Issue 7 - p 547-548 doi: 10.1097/RLU.0000000000003048 Buy Metrics Abstract The pelvis is a rare site for the origin of soft tissue sarcomas, and leiomyosarcoma remains the most common soft tissue sarcoma arising in the pelvis. Pelvic leiomyosarcomas are frequently aggressive tumors, and metastatic recurrence rates are high, with the lung, peritoneum, bone, and liver being the most frequent sites. We describe the findings of serial 18F-FDG PET/CT in a 53-year-old woman having pelvic leiomyosarcoma with uncommon site of metastasis, emphasizing the role of 18F-FDG PET/CT in response assessment. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.