Interesting ImagesDiffuse Metastases in Bilateral Penile Corpus Cavernosum From Renal Cancer Diagnosed by 18F-FDG PET/CTZou, Qiong MD*; Jiao, Ju MD*; Zou, Min-hong MD†; Yang, Ting MD*; Zhang, Yong PhD*Author Information From the Departments of *Nuclear Medicine †Ultrasonography, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China. Received for publication October 29, 2019; revision accepted January 7, 2020. Qiong Zou and Ju Jiao contributed equally to this work. Conflicts of interest and sources of funding: Qiong Zou was supported by Guangdong Medical Scientific Research Foundation (A2018047). Ju Jiao was supported by National Natural Science Fund of China (81871417). Yong Zhang was supported by Guangzhou Science and Technology Planning Project (201802020033). Other authors had no conflict of interest. Correspondence to: Yong Zhang, PhD, Department of Nuclear Medicine, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Rd, Tianhe District, Guangzhou 510630, China. E-mail: firstname.lastname@example.org. Clinical Nuclear Medicine: June 2020 - Volume 45 - Issue 6 - p 451-452 doi: 10.1097/RLU.0000000000002988 Buy Metrics Abstract We report a rare case of a 60-year-old man with diffuse metastases in bilateral penile corpus cavernosum after radical nephrectomy for left renal carcinoma. 18F-FDG PET/CT demonstrated diffuse hypermetabolic lesions in bilateral penile corpus cavernosum, hypermetabolic tumor recurrences in left renal operation region, and left pulmonary metastasis. Biopsy confirmed penile metastasis from renal clear cell carcinoma. Diffuse penile metastatic carcinoma from renal cancer is extremely rare and associated with poor prognosis. 18F-FDG PET/CT is helpful for diagnosis of penis metastasis and accurate staging of primary cancer. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.