Interesting ImagesCulprit Tumor as an Unexpected Extraosseous MDP Activity on Bone Scintigraphy in a Patient With Tumor-Induced OsteomalaciaXia, Xiaotian MD, PhD; Shao, Fuqiang MD; Hu, Fan MD; Gai, Yongkang PhD; Lan, Xiaoli MD, PhDAuthor Information From the Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology; and Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China. Received for publication February 3, 2020; revision accepted February 21, 2020. Conflicts of interest and sources of funding: This research was supported by National Natural Science Foundation of China (81801737) and fundamental research fund from the Chinese Central Universities of Huazhong University of Science and Technology (2017KFYXJJ246). None declared to all authors. Correspondence to: Xiaoli Lan, MD, PhD, Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei, China. E-mail: email@example.com; LXL730724@hotmail.com. Clinical Nuclear Medicine: June 2020 - Volume 45 - Issue 6 - p 492-494 doi: 10.1097/RLU.0000000000003042 Buy Metrics Abstract A 39-year-old man with bone pain underwent 99mTc-MDP bone scan to assess skeletal lesions, which demonstrated multiple fractures and a focus of subtle extraosseous activity in the left thigh. A 99mTc-hynic-octreotide imaging was performed due to the suspected diagnosis of tumor-induced osteomalacia, which revealed a hypermetabolic subcutaneous nodule in the left thigh, which exactly corresponded to the same site of MDP activity. Biopsy confirmed the subcutaneous nodule as the culprit tumor of tumor-induced osteomalacia. Bone scan, as a conventional imaging, provided useful information for detecting culprit tumor as shown in our case. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.