Interesting ImagesColon Adenocarcinoma Associated With Clostridium Septicum Endophthalmitis Detected on 18F-FDG PET/CTPlouznikoff, Nicolas MD, PhD, FRCPC*,†; Artigas, Carlos MD*; Woff, Erwin MD*; Ene, Diana MD‡; Flamen, Patrick MD, PhD*Author Information From the *Department of Nuclear Medicine, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium †Department of Nuclear Medicine, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada ‡Department of Nuclear Medicine, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium. Received for publication November 17, 2019; revision accepted February 16, 2020. Conflicts of interest and sources of funding: N.P. is a recipient of a Detweiler Travelling Fellowship provided by the Royal College of Physicians and Surgeons of Canada. Contributions: Dr Plouznikoff read the PET/CT and drafted the manuscript. Dr Artigas prepared the figure and reviewed the manuscript. Dr Woff interviewed the patient and reviewed the manuscript. Dr Ene followed up on the case and reviewed the manuscript. Dr Flamen revised the manuscript for important intellectual content. Correspondence to: Nicolas Plouznikoff, MD, PhD, FRCPC, Service de Médecine Nucléaire, Centre Hospitalier de l'Université de Montréal, 1051 rue Sanguinet, Montréal, QC, H2X 0C1, Canada. E-mail: firstname.lastname@example.org. Online date: April 23, 2020 Clinical Nuclear Medicine: June 2020 - Volume 45 - Issue 6 - p 459-460 doi: 10.1097/RLU.0000000000003025 Buy Metrics Abstract Endogenous Clostridium septicum endophthalmitis is a rare and fulminant ocular infection, usually encountered in immunocompromised or diabetic patients. It is also highly associated with both gastrointestinal and hematologic malignancies. We describe herein the detection of an adenocarcinoma of the cecum on PET/CT with 18F-FDG in a patient with an active endogenous C. septicum endophthalmitis of the right eye. FDG PET/CT should be considered for all patients with endogenous endophthalmitis to exclude an occult malignancy, especially colorectal cancer. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.