Interesting Images68Ga–Prostate-Specific Membrane Antigen Uptake in Dissecting Abdominal Aortic AneurysmWong, Veronica Chi Ken MBBS, FRACP*,†; Yip, Joshua Wei Liang MBBS*; Stevanovic, Amanda MBBS, FRACP†,‡; Le, Ken MBBS, FRANZCR*,†; Mansberg, Robert MBBS, FRACP, FAANMS*,†Author Information From the *Department of Nuclear Medicine and PET, Nepean Hospital, Kingswood †School of Medicine, University of Sydney, Sydney ‡Department of Medical Oncology, Nepean Hospital, Kingswood, New South Wales, Australia. Received for publication November 15, 2019; revision accepted December 22, 2019. Conflicts of interest and sources of funding: none declared. Correspondence to: Robert Mansberg, MBBS, FRACP, FAANMS, Nuclear Medicine and PET Department, Nepean Hospital, Derby St, Kingswood, New South Wales 2747, Australia. E-mail: email@example.com. Clinical Nuclear Medicine: June 2020 - Volume 45 - Issue 6 - p 455-458 doi: 10.1097/RLU.0000000000002972 Buy Metrics Abstract An 81-year-old man with prostate adenocarcinoma (Gleason 4 + 3 = 7) treated with brachytherapy and intermittent androgen deprivation therapy was referred for serial 68Ga–prostate-specific membrane antigen (PSMA-HBED-CC) PET/CT scans for rising prostate-specific antigen. Findings were suggestive of local prostatic recurrence and nodal metastases. An incidental PSMA-avid focus was noted in the anterior wall of an infrarenal aortic aneurysm, with a contrast-enhanced hyperdense region surrounded by a semilunar hypodense region anteriorly, consistent with enlarging dissecting thrombus. Increased PSMA avidity in atherosclerotic hypertensive lesions may relate to active plaque instability, indicating a need for further evaluation. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.