Interesting ImagesIncidental Detection of Hypothyroidism on 68Ga-PSMA-HBED-CC PET/CT ImagingSood, Apurva MD; Vadi, Shelvin Kumar MD; Kumar, Rajender MD; Singh, Harmandeep MD; Mittal, Bhagwant Rai MD, DNB Author Information From the Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India. Received for publication November 8, 2019; revision accepted December 9, 2019. Conflicts of interest and sources of funding: none declared. Correspondence to: Bhagwant Rai Mittal, MD, DNB, Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India. E-mail: [email protected]. Clinical Nuclear Medicine: April 2020 - Volume 45 - Issue 4 - p e217-e218 doi: 10.1097/RLU.0000000000002965 Buy Metrics Abstract 68Ga-labeled prostate-specific membrane antigen (PSMA) ligand PET/CT is a rapidly evolving imaging modality for prostate cancer. However, with the widespread use of 68Ga-PSMA PET/CT, various reports of nonprostatic uptake of 68Ga-PSMA in both benign and malignant lesions have also appeared. We report a recently diagnosed case of prostate cancer demonstrating diffuse 68Ga-PSMA expression in both the lobes of thyroid gland, which on further clinical and biochemical investigations was established as hypothyroidism. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.