Interesting ImagesPseudomyogenic Hemangioendothelioma Distinctive FDG PET/CT Findings With Numerous Multilayer Lesions in a Single Distal ExtremityLiu, Yiyan MD, PhDAuthor Information From the Nuclear Medicine Service, Department of Radiology, New Jersey Medical School, Rutgers University, Newark, NJ. Received for publication October 1, 2019; revision accepted October 14, 2019. Conflicts of interest and sources of funding: none declared. Correspondence to: Yiyan Liu, MD, PhD, Nuclear Medicine Service, Department of Radiology, University Hospital, H-141, 150 Bergen St, Newark, NJ 07103. E-mail: email@example.com. Online date: January 30, 2019 Clinical Nuclear Medicine: March 2020 - Volume 45 - Issue 3 - p 248-249 doi: 10.1097/RLU.0000000000002895 Buy Metrics Abstract Pseudomyogenic hemangioendothelioma is a rare vascular tumor described as a fibroma-like variant of epithelioid sarcoma. There were scant publications about FDG PET/CT findings of pseudomyogenic hemangioendothelioma. A 20-year-old man with biopsy-confirmed pseudomyogenic hemangioendothelioma of the left tibia had FDG PET/CT for evaluation of the lesion extent and metastasis, which demonstrated numerous, multilayer FDG-avid lesions of the left lower extremity below the knee. Although pathologic examination is mandatory for diagnosis, FDG PET/CT of the case showed distinctive image finding of pseudomyogenic hemangioendothelioma: multifocal and multilayer lesions in a single distal lower extremity. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.