Interesting ImagesPosttreated POEMS Syndrome With Concurrent Follicular Lymphoma Revealed by 18F-FDG and 68Ga-Pentixafor PET/CTPan, Qingqing MD*,†; Luo, Yaping MD*,†; Cao, Xinxin MD‡; Li, Jian MD‡; Li, Fang MD*,†Author Information From the *Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital †Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine ‡Department of Hematology, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, Beijing, China. Received for publication October 11, 2019; revision accepted November 12, 2019. Conflicts of interest and sources of funding: This work is supported by the National Natural Science Foundation of China (81701741). None declared to all authors. Correspondence to: Yaping Luo, MD, Department of Nuclear Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College Hospital, 1 Shuaifuyuan Wangfujing, Dongcheng District, Beijing 100730, China. E-mail: email@example.com. Online date: January 30, 2019 Clinical Nuclear Medicine: March 2020 - Volume 45 - Issue 3 - p 220-222 doi: 10.1097/RLU.0000000000002923 Buy Metrics Abstract A 59-year-old man with history of POEMS syndrome was found with a painless mass in the right neck for 9 months. In 18F-FDG and 68Ga-pentixafor PET/CT, there were multiple neck nodes and left inguinal nodes that showed intense 18F-FDG and 68Ga-pentixafor uptake. In addition, osteoblastic bone lesions with mild 18F-FDG and 68Ga-pentixafor uptake were noted in the pelvis, which was consistent with posttreated osseous involvement of POEMS syndrome. However, considering lymphoadenopathy with such intense 18F-FDG uptake is not usually seen in POEMS syndrome, the patient underwent biopsy of the right cervical nodes. The histopathology with immunohistochemistry confirmed follicular lymphoma. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.