Interesting ImagesNodular Fat-Sparing Hepatic Parenchyma as 11C-Choline–Avid Finding on PET/CTNguyen, Ba Duong MD; Heller, Matthew T. MD; Roarke, Michael C. MDAuthor Information From Mayo Clinic, Scottsdale, AZ. Received for publication July 26, 2019; revision accepted October 13, 2019. Conflicts of interest and sources of funding: none declared. Correspondence to: Ba Duong Nguyen, MD, Mayo Clinic, Department of Radiology, 13400 E. Shea Blvd, Scottsdale, AZ 85259. E-mail: email@example.com. Online date: January 30, 2019 Clinical Nuclear Medicine: March 2020 - Volume 45 - Issue 3 - p 228-229 doi: 10.1097/RLU.0000000000002898 Buy Metrics Abstract Focal nodular fat sparing of the liver may show, on PET/CT imaging, prominent tracer uptake over a background of less metabolic features of steatosis. This finding, already reported with 18F-FDG, may mimic primary or secondary neoplasms of the liver. The authors present an additional case of nodular fat-sparing hepatic parenchyma exhibiting 11C-choline avidity during PET/CT assessment for biochemical recurrence of prostate cancer. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.