Interesting ImagesDiffuse Hepatosplenic 99mTc-Pyrophosphate Activity Caused by AmyloidosisRen, Jingyun MD*; Ren, Chao MD*; Huo, Li MD, PhD*; Li, Fang MD*; Zhang, Shuyang MD†Author Information From the *Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine †Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Received for publication September 28, 2019; revision accepted October 4, 2019. Conflicts of interest and sources of funding: This work was sponsored in part by the National Key Research and Development Program of China (grant no. 2016YFC0901500) and CAMS Innovation Fund for Medical Sciences CIFMS (grant 2016-I2M-4-003, 2018-I2M-3-001). None declared to all authors. Correspondence to: Fang Li, MD, Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, #1 Shuaifuyuan, Dongcheng District, Beijing, China 100730. E-mail: Lifang@pumch.cn. Online date: January 30, 2019 Clinical Nuclear Medicine: March 2020 - Volume 45 - Issue 3 - p 246-247 doi: 10.1097/RLU.0000000000002877 Buy Metrics Abstract A 46-year-old man underwent 99mTc-pyrophosphate scan to evaluate possible infiltrative myocardiopathy revealed by echocardiography. The images did not show abnormal cardiac activity. However, diffuse abnormal activity in the liver and spleen was noted. Pathological examination from the specimen acquired from hepatic biopsy demonstrated amyloidosis, light chain type. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.