Interesting ImagesBilateral End-Organ Endophthalmitis in Setting of Serratia marcescens Urosepsis on 18F-FDG PET/CTMakusha, Lovemore P. BA*; Young, Colin R. MD†; Agarwal, Daniel R. MD‡; Pucar, Darko MD†Author Information From the *Medical Doctorate Program †Department of Radiology and Imaging ‡Department of Ophthalmology, Yale University School of Medicine, New Haven, CT. Received for publication June 6, 2019; revision accepted October 7, 2019. Conflicts of interest and sources of funding: none declared. Correspondence to: Lovemore P. Makusha, BA, Medical Doctorate Program, Yale School of Medicine, 333 Cedar St, New Haven, CT 06511. E-mail: email@example.com. Online date: December 24, 2019 Clinical Nuclear Medicine: March 2020 - Volume 45 - Issue 3 - p e141-e143 doi: 10.1097/RLU.0000000000002883 Buy Metrics Abstract Endogenous endophthalmitis is an uncommon infection of the internal tissues of the eye resulting from a bloodborne infection. We present the case of an 89-year-old man with Serratia marcescens urosepsis with multifocal end-organ infection on 18F-FDG PET/CT including aortitis, splenic abscess, septic arthritis, thoracolumbar discitis-osteomyelitis, and culture-confirmed bilateral endogenous endophthalmitis. Endophthalmitis-related intraconal ocular space uptake was clearly distinguishable from normal conal space extraocular muscle activity. Although sepsis responded to treatment, endophthalmitis led to complete vision loss. This case report presents PET/CT description of a rare and difficult-to-treat Serratia marcescens endogenous endophthalmitis, which usually has a poor visual outcome. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.