Interesting Images68Ga–Prostate-Specific Membrane Antigen Uptake in Cerebral TuberculosisWong, Veronica Chi Ken MBBS, FRACP*,†; Shen, Lily MBBS, FRACP, FAANMS*; Nasser, Elias MBBS, MRCP(UK), FRANZCR‡,§; Adams, David Nicholas MBBS, FRACP§,∥; Mansberg, Robert MBBS, FRACP, FAANMS*,†Author Information From the *Department of Nuclear medicine and PET, Nepean Hospital, Kingswood †School of Medicine, University of Sydney, Sydney ‡Department of Radiation Oncology, The Wollongong Hospital §Graduate School of Medicine, University of Wollongong ∥Department of Infectious Diseases, The Wollongong Hospital, Wollongong, New South Wales, Australia. Received for publication September 25, 2019; revision accepted October 27, 2019. Conflicts of interest and sources of funding: none declared. Correspondence to: Robert Mansberg, MBBS, FRACP, FAANMS, Nuclear Medicine and PET Department, Nepean Hospital, Derby St, Kingswood, New South Wales 2747, Australia. E-mail: firstname.lastname@example.org. Online date: January 30, 2019 Clinical Nuclear Medicine: March 2020 - Volume 45 - Issue 3 - p 238-240 doi: 10.1097/RLU.0000000000002910 Buy Metrics Abstract A 71-year-old man with a history of high-risk prostate adenocarcinoma (Gleason score 4 + 5 = 9) treated with brachytherapy in 2016 was referred for a 68Ga–prostate-specific membrane antigen (PSMA)–HBED–CC PET/CT scan for suspected cancer recurrence on a background of slowly rising serum prostate-specific antigen (0.95 ng/mL; reference, <0.2 ng/mL). This revealed PSMA-avid dura-based hyperdense lesions in the brain, suggestive of cerebral metastases. Biopsy demonstrated the presence of acid-fast bacilli, and with further clinical and microbiological testing, a diagnosis of PSMA-avid cerebral tuberculous mycobacterium infection was made. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.