Interesting ImagesThe Detection of Cardiac Adrenocorticotropic Hormone–Secreting Neuroendocrine Tumor With the Help of 68Ga-DOTATATE PET/CTHou, Guozhu MD; Jiang, Yuanyuan MD; Cheng, Xin MDAuthor Information From the Department of Nuclear Medicine, Peking Union Medical College Hospital Chinese Academy of Medical Sciences and Peking Union Medical College; and Beijing Key Laboratory of Molecular Targeted Diagnosis and Therapy in Nuclear Medicine, Beijing, China. Received for publication July 5, 2019; revision accepted October 13, 2019. G.H. and Y.J. contributed equally to this work. Conflicts of interest and sources of funding: This work is supported by CAMS Initiative for Innovative Medicine (CAMS-2018-I2M-3-001). No conflicts of interest declared to all authors. Correspondence to: Xin Cheng, MD, Department of Nuclear Medicine, Peking Union Medical College Hospital, No. 1 Shuaifuyuan, Wangfujing, Dongcheng District, Beijing 100730, China. E-mail: email@example.com. Online date: December 24, 2019 Clinical Nuclear Medicine: February 2020 - Volume 45 - Issue 2 - p 136-138 doi: 10.1097/RLU.0000000000002892 Buy Metrics Abstract Ectopic adrenocorticotropic hormone Cushing syndrome is a relatively rare condition. We present the case of a 39-year-old man with ectopic adrenocorticotropic hormone Cushing syndrome due to a cardiac neuroendocrine tumor (NET), which was localized with the help of 68Ga-DOTATATE. 18F-FDG PET/CT revealed a hypermetabolic lesion in the heart, while the distinction between physiological and pathological FDG uptake is difficult. 68Ga-DOTATATE PET/CT revealed focal uptake corresponding to the cardiac focus found on FDG PET/CT, providing evidence of cardiac NET. This case illustrates that 68Ga-DOTATATE could play a role in the evaluation of cardiac NET as it lacks significant physiological myocardial uptake. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.