Interesting Images18F-FDG PET in Giant Cell ArteritisAhmadi Bidakhvidi, Niloefar MD*; Goffin, Karolien MD, PhD*; Van Laere, Koen MD, PhD DrSc*; Gheysens, Olivier MD, PhD*; Blockmans, Daniel MD, PhD†Author Information From the *Nuclear Medicine and Molecular Imaging †Internal Medicine, University Hospitals Leuven, UZ Leuven, Belgium. Received for publication September 11, 2019; revision accepted October 16, 2019. Conflicts of interest and sources of funding: none declared. Correspondence to: Niloefar Ahmadi Bidakhvidi, MD, Department of Nuclear Medicine, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium. E-mail: email@example.com. Online date: December 24, 2019 Clinical Nuclear Medicine: February 2020 - Volume 45 - Issue 2 - p 170-171 doi: 10.1097/RLU.0000000000002903 Buy Metrics Abstract An 87-year-old man, without significant history, presented at the emergency department with recurrent episodes of fever and weight loss for several weeks without diagnosis, despite extensive routine investigations including conventional imaging. 18F-FDG PET/CT revealed strongly increased uptake in the peripheral vessels of the upper and lower limbs with relative sparing of the larger vessels. Temporal artery biopsy was positive for arteritis. The diagnosis of giant cell arteritis with mainly involvement of upper and lower limbs was made, and treatment with high-dose oral methylprednisolone was started, resulting in a rapid clinical and biochemical improvement. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.