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Orbital Adult T-Cell Leukemia/lymphoma With Skin Involvement Demonstrated on FDG PET/CT

Hotta, Masatoshi MD; Minamimoto, Ryogo MD, PhD

Clinical Nuclear Medicine: December 2019 - Volume 44 - Issue 12 - p 993–994
doi: 10.1097/RLU.0000000000002773
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An 85-year-old woman presented with decreased visual acuity. MRI of the brain revealed bilateral orbital masses, and FDG-PET/CT demonstrated moderate to intense uptake in the orbital tumors and thickened skin on the left lower leg. Biopsies of the orbital and cutaneous lesions revealed infiltration by T-cell lymphoma, and the presence of human T-cell lymphotropic virus type 1 antigens confirmed the diagnosis of adult T-cell leukemia/lymphoma (ATLL). Although orbital ATLL is rare, the skin is a common site of extranodal involvement of T-cell lymphomas, including ATLL, and FDG uptake by a cutaneous lesion can facilitate early diagnosis.

From the Department of Nuclear Medicine, National Center for Global Health and Medicine, Tokyo, Japan.

Received for publication July 12, 2019; revision accepted July 12, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Masatoshi Hotta, MD, Department of Nuclear Medicine, National Center for Global Health and Medicine, 1-21-1, Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan. E-mail: masatoshihotta@yahoo.co.jp.

Online date: September 13, 2019

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