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Significantly Increased Accumulation of 18F-FDG Throughout the Left Middle Cerebral Artery Territory Corresponding to Acute-Phase Infarction

Okuyama, Chio MD, PhD*; Nakae, Takuro MD, PhD; Oka, Satoshi MD, PhD; Nohara, Jun MD§; Yamauchi, Hiroshi MD, PhD*

doi: 10.1097/RLU.0000000000002796
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A 70-year-old woman had spontaneous resolution of an embolism in her right middle cerebral artery (MCA) (day 1); another embolism occurred in her left MCA (day 3), which was promptly removed. On day 5, 18F-FDG PET/CT performed for staging mediastinal lymphoma showed marked FDG accumulation in the left MCA territory, whereas a defect was seen in the right insular region. Eventually, bilateral lesions developed irreversible infarction. Anaerobic metabolism and/or inflammation in acute-phase infarction were the supposed mechanism for the increased accumulation of FDG in her left MCA territory.

From the *Division of PET imaging, Shiga Medical Center Research Institute

Departments of Neurosurgery

Hematology and Oncology

§Respiratory Medicine, Shiga General Hospital, Moriyama, Japan.

Received for publication April 18, 2019; revision accepted July 19, 2019.

Conflicts of interest and sources of funding: This article was partly supported by the Grant-in-Aid for Scientific Research (C) from the Japan Society for the Promotion of Science only for the cost of English proofreading. The authors state that this work has not received any other funding, and there are no other conflicts of interest to disclose.

Correspondence to: Chio Okuyama, MD, PhD, Shiga Medical Center Research Institute, 5-4-30, Moriyama-cho, Moriyama, Shiga 524-8524, Japan. E-mail:

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