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Lung Perfusion Scintigraphy in Eisenmenger Syndrome Due to Patent Ductus Arteriosus

Mitsui, Kohei MD; Woodhams, Reiko MD, PhD; Ukisu, Ryutarou MD, PhD; Inoue, Yusuke MD, PhD

doi: 10.1097/RLU.0000000000002735
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Eisenmenger syndrome refers to the elevation of pulmonary arterial pressure to the systemic level caused by an increased pulmonary vascular resistance with right-to-left shunt through an intracardiac or aortopulmonary communication. A 36-year-old woman with Eisenmenger syndrome due to patent ductus arteriosus underwent 99mTc-MAA lung perfusion scintigraphy to evaluate right-to-left shunt. Whole-body imaging visualized extrapulmonary activity in both kidneys, spleen, and intestinal tract, confirming the presence of right-to-left shunt. Accumulation in the brain was visible but much weaker compared with that in the body trunk and was limited to the left cerebral hemisphere, which reflected the location of the shunt pathway.

From the Department of Diagnostic Radiology, Kitasato University School of Medicine, Kanagawa, Japan.

Received for publication March 9, 2019; revision accepted June 2, 2019.

Conflict of interest and sources of funding: none declared.

Correspondence to: Department of Radiology, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252–0374, Japan. E-mail:

Online date: July 30, 2019

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