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Giant Melanotic Malignant Peripheral Nerve Sheath Tumor in the Pelvis

Contrast-Enhanced CT and 18F-FDG PET/CT Finding

Liu, Entao MD*; Sun, Taotao MD*; Liu, Chao MD; Wang, Siyun MD, PhD*; Wang, Shuxia MD, PhD*

doi: 10.1097/RLU.0000000000002677
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Melanotic malignant peripheral nerve sheath tumor is an extremely rare tumor, which originates from the neural crest, and more than half the cases are associated with Carney complex (myxomas, spotty pigmentation, and endocrine abnormalities). Herein, we have presented a case of a melanotic malignant peripheral nerve sheath tumor, which is not associated with Carney complex. The patient underwent preoperative nonenhanced CT, contrast-enhanced CT, and 18F-FDG PET/CT scans, which showed a large pelvic tumor with heterogeneous enhancement and increased 18F-FDG uptake. Subsequently, the patient underwent complete resection of the tumor.

From the *WeiLun PET Center, Department of Nuclear Medicine

Department of Pathology and Laboratory Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, People’s Republic of China.

Received for publication April 4, 2019; revision accepted May 7, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Shuxia Wang, MD, PhD, Room 517, 5/F, WeiLun Building of Guangdong Provincial People's Hospital, 106 Zhongshan Er Road, Guangzhou 510080, Guangdong, People’s Republic of China. E-mail:

Online date: July 5, 2019

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