Approximately 5% to 15% cases of endogenous Cushing syndrome are due to ectopic adrenocorticotrophic hormone (ACTH)–producing neuroendocrine tumors, which are commonly located in bronchopulmonary system, thymus, and gastrointestinal tract including pancreas. Although carcinoid tumors of the appendix are revealed in 0.3% of patients undergoing routine appendectomy, ACTH-secreting appendicular carcinoid is a rare entity. We present a case of a 22-year-old woman with ectopic ACTH-dependent Cushing syndrome due to an appendicular carcinoid, which was localized with the help of 68Ga-DOTATATE PET/CT scan.
From the Department of Endocrinology, Seth GS Medical College, Parel, Mumbai, India.
Received for publication March 13, 2019; revision accepted July 3, 2019.
Conflicts of interest and sources of funding: none declared.
Correspondence to: Tushar Bandgar, DM, Department of Endocrinology, Seth GS Medical College & KEMH, Parel, Mumbai 400012, India. E-mail: email@example.com.
Online date: September 13, 2019