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18F-FDG PET/CT in Metastatic Extramammary Paget’s Disease

Khoo, Alex Cheen Hoe MBBS, MMed, FANMB*; Yeoh, Kheng Wei MSc, MBBS, MRCP, MPH, FRCR

doi: 10.1097/RLU.0000000000002739
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Extramammary Paget's disease (EMPD) is a rare disease with an estimated prevalence of 0.1 to 2.4 per 1,000,000 person-years. Metastatic EMPD has a poor prognosis with a 5-year survival of approximately 7%. Local therapy is the only curative option with surgery being recommended for resectable disease. It is therefore crucial to be able to stage such patients appropriately. The utility of 18F-FDG PET/CT for this disease is not well established. We share a case on how 18F-FDG PET/CT was used to stage metastatic EMPD.

From the Departments of *Nuclear Medicine

Oncology, Penang Adventist Hospital, George Town, Penang, Malaysia.

Received for publication March 14, 2019; revision accepted June 5, 2019.

The manuscript has not been published before or is not under consideration for publication anywhere else and has been approved by all co-authors.

Conflicts of interest and sources of funding: none declared.

Ethical Statement: The study was approved by an institutional review board or equivalent and has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. The subject in the study gave written informed consent.

Authors' Contribution: Khoo proposed and co-wrote the manuscript. Yeoh co-wrote the manuscript. Both reviewed the final manuscript.

Correspondence to: Alex Khoo Cheen Hoe, MBBS, MMed, FANMB, Department of Nuclear Medicine, Penang Adventist Hospital, 456, Jalan Burma 10350 Georgetown, Penang, Malaysia. E-mail:

Online date: July 25, 2019

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