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FDG-Avid Hürthle Cell Thyroid Adenoma

Yu, Run MD, PhD*; Auerbach, Martin S. MD

doi: 10.1097/RLU.0000000000002617
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Incidental thyroid uptake is found in approximately 2.5% of patients who undergo FDG PET for nonthyroid malignancy; approximately a third of the FDG PET thyroid incidentalomas are malignant, including primary thyroid malignancies and metastasis. We describe a 50-year-old woman, a potential heart transplant candidate with history of breast cancer, who was found by FDG PET/CT to harbor a large thyroid mass with intense FDG uptake. Biopsy and molecular study demonstrated that the thyroid mass was a Hürthle cell adenoma. This case highlights that Hürthle cell neoplasm should be included in the differential diagnosis of a thyroid nodule with very high FDG avidity.

From the *Division of Endocrinology

Department of Nuclear Medicine and Department of Molecular and Medical Pharmacology, UCLA David Geffen School of Medicine, Los Angeles, CA.

Received for publication March 3, 2019; revision accepted March 30, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Run Yu, MD, PhD, Division of Endocrinology, UCLA David Geffen School of Medicine, 200 Medical Plaza Dr, Suite 530, Los Angeles, CA 90095. E-mail:

Online date: May 30, 2019

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