Incidental thyroid uptake is found in approximately 2.5% of patients who undergo FDG PET for nonthyroid malignancy; approximately a third of the FDG PET thyroid incidentalomas are malignant, including primary thyroid malignancies and metastasis. We describe a 50-year-old woman, a potential heart transplant candidate with history of breast cancer, who was found by FDG PET/CT to harbor a large thyroid mass with intense FDG uptake. Biopsy and molecular study demonstrated that the thyroid mass was a Hürthle cell adenoma. This case highlights that Hürthle cell neoplasm should be included in the differential diagnosis of a thyroid nodule with very high FDG avidity.
From the *Division of Endocrinology
†Department of Nuclear Medicine and Department of Molecular and Medical Pharmacology, UCLA David Geffen School of Medicine, Los Angeles, CA.
Received for publication March 3, 2019; revision accepted March 30, 2019.
Conflicts of interest and sources of funding: none declared.
Correspondence to: Run Yu, MD, PhD, Division of Endocrinology, UCLA David Geffen School of Medicine, 200 Medical Plaza Dr, Suite 530, Los Angeles, CA 90095. E-mail: firstname.lastname@example.org.
Online date: May 30, 2019