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Utility of 18F-FDG PET/CT in Infantile Myofibromatosis

Tang, Elizabeth R. MD*; Khalatbari, Hedieh MD*; Parisi, Marguerite T. MD, MS*,†

doi: 10.1097/RLU.0000000000002627
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Infantile myofibromatosis, a rare, nonmalignant disease seen almost exclusively in the pediatric population, can involve skin, muscle, soft tissues, bone, or viscera in either solitary or multicentric pattern. Although nonmalignant, visceral involvement in infantile myofibromatosis is a key prognostic indicator, which is associated with mortality in 75% of patients. Those with pulmonary involvement have a particularly poor outcome. This case illustrates the diagnostic utility of 18F-FDG PET/CT in defining disease extent in this unusual entity and compares it to other commonly used imaging modalities.

From the Departments of *Radiology

Pediatrics, University of Washington School of Medicine, and Seattle Children's Hospital, Seattle, WA.

Received for publication February 14, 2019; revision accepted March 23, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Marguerite T. Parisi, MD, MS, Department of Radiology, MS# MA.7.770, Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA 98105. E-mail: meg.parisi@seattlechildrens.org.

Online date: May 30, 2019

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