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Thyroid Incidentaloma on 18F-fluorocholine PET/CT and 68Ga-PSMA PET/CT Revealing a Medullary Thyroid Carcinoma

Ciappuccini, Renaud MD*,†; Edet-Sanson, Agathe MD; Saguet-Rysanek, Virginie MD§; Gauthé, Mathieu MD; Bardet, Stéphane MD*

doi: 10.1097/RLU.0000000000002559
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A 66-year-old man with prostate cancer underwent 18F-fluorocholine PET/CT and thereafter 68Ga-labeled prostate-specific membrane antigen PET/CT to explore a rising prostate-specific antigen level. Both PET/CT studies showed a thyroid incidentaloma of the right lobe. Neck ultrasound confirmed the presence of a 16-mm right thyroid nodule. The serum calcitonin level was moderately increased at 25 ng/mL (<10). Cytology was non-diagnostic (Bethesda I). A right lobectomy was performed and pathology revealed a 15-mm medullary thyroid cancer. Two months after surgery, the calcitonin level returned to normal at 3.3 ng/mL.

From the *Department of Nuclear Medicine and Thyroid Unit, François Baclesse Cancer Centre, Caen

INSERM U1086 ANTICIPE, Normandie University, Caen

Department of Nuclear Medicine, Henri Becquerel Cancer Centre, Rouen

§Department of Pathology, François Baclesse Cancer Centre, Caen

Department of Nuclear Medicine, Tenon Hospital, AP-HP, Paris, France.

Received for publication February 4, 2019; revision accepted February 11, 2019.

Conflicts of interest and sources of funding: none declared.

Informed consent: Written informed consent was obtained from the patient.

Correspondence to: Dr Renaud Ciappuccini, MD, Department of Nuclear Medicine and Thyroid Unit François Baclesse Cancer Centre, 3 Avenue Général Harris, F-14000 Caen, France. E-mail: r.ciappuccini@baclesse.unicancer.fr.

Online date: April 15, 2019

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