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Rapid Decomposition of 99mTc-MAA Complex During Lung Perfusion Imaging

Ajdari, Sadegh Ebrahim MD; Qutbi, Mohsen MD

doi: 10.1097/RLU.0000000000002643
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A 30-year-old woman with a recent episode of dyspnea was presented. The lung perfusion scan using 99mTc-MAA (macro-aggregated albumin) initially revealed an acceptable lung-to-background activity ratio implying a proper radiopharmaceutical preparation and radiolabeling efficiency. Unexpectedly, later during the scan, rapidly increasing concentration of activity was observed in salivary glands, thyroid and stomach. Rapid breakdown of 99mTc-MAA complexes was considered as a likely explanation for the increase in the circulatory level of the free pertechnetate.

From the Department of Nuclear Medicine, Taleghani Educational Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Received for publication February 7, 2019; revision accepted April 22, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Mohsen Qutbi, Department of Nuclear Medicine, Taleghani Hospital, Yaman St., Velenjak, Tehran 1985711151, Iran. E-mail:,

Online date: June 14, 2019

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