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Parathyroid Glands Hyperplasias Mimicking Medullary Thyroid Carcinoma Metastatic Lymph Nodes on 18F-DOPA PET/CT

Terroir, Marie MD*; Grimaldi, Serena MD*; Hartl, Dana MD; Leboulleux, Sophie MD*; Deandreis, Désirée MD*,†,‡

doi: 10.1097/RLU.0000000000002633
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A pre operatory assessment by neck US, 18F-DOPA and 18F-choline PET/CT was performed in a 43-year-old MEN 2A woman affected by hyperparathyroidism and medullary thyroid carcinoma (MTC). On 18F-DOPA, two thyroid uptakes were analyzed as multifocal MTC and two others in the central neck compartment as MTC metastatic lymph nodes. After surgery, multifocal intra thyroidal MTC and two parathyroid glands hyperplasias were proved without MTC adenopathies. We report a case of rare false positive uptake on 18F-DOPA. In case of several endocrine diseases coexistence as in MEN 2A, 18F-DOPA should be carefully analyzed.

From the Departments of *Nuclear Medicine and Endocrine Oncology,

Surgery, Gustave Roussy and Université Paris Saclay, Villejuif, France

Department of Medical Sciences, University of Turin, Turin, Italy.

Received for publication February 14, 2019; revision accepted April 19, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Marie Terroir, MD, 114 rue Edouard vaillant, 94805 Villejuif, France. E-mail:

Online date: June 3, 2019

Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.