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False-Positive 68Ga-DOTATATE PET/CT in Active Chronic Prostatitis

Yilmaz, Burcak MD*; Arslan, Hilal Serap MD; Gundogan, Cihan MD*; Gunes, Mehmet Nuri MD; Cermik, Tevfik Fikret MD*

doi: 10.1097/RLU.0000000000002594
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A 66-year-old man with neuroendocrine tumor originating from midgut was referred to 68Ga-DOTATATE PET/CT imaging for restaging postoperatively. No suspicious uptake regarding residual primary tumoral involvement was seen. But there was diffuse high uptake in prostate gland suggestive of prostatitis or secondary primary tumoral lesion. Concurrent prostate-specific antigen level was 5.02 ng/mL (range, 0–4 ng/mL), C-reactive protein level was 8.25 mg/L (range, <5 mg/L), and white blood cell count was 6.83 × 103/μL (range, 3.9–10.9 × 103/μL). Diagnosis of active chronic prostatitis was achieved by core biopsy, which is identified as potential cause for false-positive diffuse uptake on 68Ga-DOTATATE PET/CT.

From the *Nuclear Medicine Department, Istanbul Research and Training Hospital

Pathology Department

Urology Department, Kanuni Sultan Suleyman Research and Training Hospital, Health Sciences University, Istanbul, Turkey.

Received for publication February 16, 2019; revision accepted March 14, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Burcak Yilmaz, MD, Nuclear Medicine Department, Istanbul Research and Training Hospital, Health Sciences University, Org. Abdurrahman Nafiz Gürman Cad. Etyemez, Samatya, 34098 Istanbul, Turkey. E-mail:

Online date: April 15, 2019

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