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Alveolar Sarcoidosis With Intense FDG Uptake, Mimicking Multi-focal Pneumonia and Infiltrative Lung Malignancy

Ansari-Gilani, Kianoush MD; Yang, Michael MD; Ramaiya, Nikhil H. MD

doi: 10.1097/RLU.0000000000002637
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Alveolar sarcoidosis is an uncommon radiologic manifestation of pulmonary sarcoidosis which appears as infiltrative or mass-like opacities mimicking multifocal pneumonia or infiltrative lung malignancies such as multi-focal adenocarcinoma or pulmonary lymphoma. It has correlation with a more acute and symptomatic phase of thoracic sarcoidosis and therefore expected to show a more severely increased metabolic activity on FDG PET. Alveolar sarcoidosis shows a relatively rapid radiological improvement after initiation of corticosteroid therapy. Tissue diagnosis might be needed in some cases to exclude malignancy.

From the Radiology Department, University Hospital Cleveland Medical Center, Cleveland, OH.

Received for publication January 7, 2019; revision accepted April 22, 2019.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Kianoush Ansari-Gilani, MD, Radiology Department, University Hospital Cleveland Medical Center, 11100 Euclid Avenue, Cleveland, OH 44124. E-mail:

Online date: June 3, 2019

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