We report the case of a 62-year-old woman with previous history of stage III Hodgkin lymphoma. Routine follow-up CT scan revealed 2 years after end of treatment the appearance of mediastinal nodes, suspected of lymphoma recurrence. An 18F-FDG PET/CT was performed showing hypermetabolic mediastinal lymph nodes with diffuse symmetric osteomedullar hypermetabolism of pelvis and scapulae. In the hypothesis of either recurrence or multisystemic inflammatory disorder, bone marrow and lymph node biopsies were performed, revealing the presence of noncaseating epithelioid cell granulomas, leading to the diagnosis of multisystemic sarcoidosis. This case illustrates the sarcoidosis-lymphoma syndrome.
From the Department of Nuclear Medicine, Institut Curie, PSL Research University, Paris, France.
Received for publication November 21, 2018; revision accepted May 1, 2019.
Conflicts of interest and sources of funding: none declared.
Correspondence to: Aurélie Bando-Delaunay, MD, Department of Nuclear Medicine, Institut Curie, PSL Research University, F-75005 Paris, France. E-mail: firstname.lastname@example.org.
Online date: June 3, 2019