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The Finding of the “Mini Brain” May Not Be a Unique Anatomic Appearance of Spinal Plasmacytoma

Zhong, Xiao, MD; Jia, Zhiyun, MD; Su, Minggang, MD

doi: 10.1097/RLU.0000000000002632
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MRI and 18F-FDG PET/CT were performed on a 37-year-old man who was suspected with malignant spinal tumor on x-ray examination. An FDG-avid expansile lytic lesion was found in his T12 vertebra. The lesion showed a characteristic “mini-brain” appearance on MRI and CT. This extremely high specificity sign and consistent manifestation on PET image indicated plasmacytoma as the most optimal diagnosis. But finally, a giant cell tumor was confirmed after surgery. The case cautions that the specificity of the diagnostic characteristics of “mini-brain” sign for plasmacytoma or multiple myeloma may not be as high as previously reported.

From the Department of Nuclear Medicine, West China Hospital of Sichuan University, Chengdu, Sichuan, People's Republic of China.

Received for publication January 30, 2019; revision accepted April 10, 2019.

Xiao Zhong and Zhiyun Jia attributed equally to the work.

Conflicts of interest and sources of funding: none declared.

Correspondence to: Minggang Su, MD, From the Department of Nuclear Medicine, West China Hospital of Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, China. E-mail: suminggang@sina.com.

Online date: May 30, 2019

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