We evaluated the reproducibility of 123I-ioflupane (123I-FP-CIT) SPECT with shorter scan times using a CZT camera. One hundred ninety-nine 123I-FP-CIT SPECT scans obtained with standard scan time (30 minutes) were truncated to provide 24-, 18-, and 15-minute study simulations. Striatal binding ratios were automatically calculated and remained stable for all series. At 15 minutes, only 10 of 398 striata (2.5%) showed statistically significant different striatal binding ratios compared with reference series. These series were reviewed by 2 operators, and a perfect agreement was found for each patient. Therefore, CZT camera allows a 2-fold scan time reduction in 123I-FP-CIT SPECT.
From the *Service de Médecine Nucléaire, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron;
†Service de Physique Médicale et Radioprotection, Groupement Hospitaliers Est, Hospices Civils de Lyon, Bron; and
‡Université Claude Bernard Lyon 1, Villeurbanne, France.
Received for publication July 29, 2018; revision accepted February 7, 2019.
Conflicts of interest and sources of funding: C.S. is invited to give lectures for the General Electric. A.B.S., N.T., and P.T. have nothing to disclose.
Correspondence to: Alexandre Bani-Sadr, MD, MSc, Service de Médecine Nucléaire, Groupement Hospitalier Est, Hospices Civils de Lyon, 28 avenue Doyen Lépine, 69500 Bron, France. E-mail: firstname.lastname@example.org.
Online date: April 1, 2019