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Reduced Scan Time in 123I-FP-CIT SPECT Imaging Using a Large-Field Cadmium-Zinc-Telluride Camera

Bani Sadr, Alexandre, MD, MSc*; Testart, Nathalie, MD*; Tylski, Perrine, PhD; Scheiber, Christian, MD, PhD*‡

doi: 10.1097/RLU.0000000000002554
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We evaluated the reproducibility of 123I-ioflupane (123I-FP-CIT) SPECT with shorter scan times using a CZT camera. One hundred ninety-nine 123I-FP-CIT SPECT scans obtained with standard scan time (30 minutes) were truncated to provide 24-, 18-, and 15-minute study simulations. Striatal binding ratios were automatically calculated and remained stable for all series. At 15 minutes, only 10 of 398 striata (2.5%) showed statistically significant different striatal binding ratios compared with reference series. These series were reviewed by 2 operators, and a perfect agreement was found for each patient. Therefore, CZT camera allows a 2-fold scan time reduction in 123I-FP-CIT SPECT.

From the *Service de Médecine Nucléaire, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron;

Service de Physique Médicale et Radioprotection, Groupement Hospitaliers Est, Hospices Civils de Lyon, Bron; and

Université Claude Bernard Lyon 1, Villeurbanne, France.

Received for publication July 29, 2018; revision accepted February 7, 2019.

Conflicts of interest and sources of funding: C.S. is invited to give lectures for the General Electric. A.B.S., N.T., and P.T. have nothing to disclose.

Correspondence to: Alexandre Bani-Sadr, MD, MSc, Service de Médecine Nucléaire, Groupement Hospitalier Est, Hospices Civils de Lyon, 28 avenue Doyen Lépine, 69500 Bron, France. E-mail:

Online date: April 1, 2019

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