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18F-FDG PET/CT for Staging and Evaluation of Therapy in a Patient With Unusual Hairy Cell Leukemia Presentation

Doma, Andrej, MD*; Škerget, Matevž, MD, PhD; Žagar, Ivana, MD, PhD*

doi: 10.1097/RLU.0000000000002557
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Hairy cell leukemia is a rare hematologic malignancy characterized by splenomegaly, pancytopenia, and susceptibility to infections. We report a case of a 66-year-old man, diagnosed with hairy cell leukemia, without severe cytopenias and splenomegaly, but with an extensive pathological retroperitoneal mass and infiltration of the spleen and skeletal involvement. All findings were highly avid on pretreatment 18F-FDG PET/CT scan. Treatment response evaluation 18F-FDG PET/CT scan showed normalization of FDG uptake on all previously pathological sites.

From the *Department of Nuclear Medicine, Institute of Oncology Ljubljana, Ljubljana; and

Department of Hematology, University Medical Centre Ljubljana, Slovenia.

Received for publication February 1, 2019; revision accepted February 10, 2019.

Conflicts of interest and sources of funding: none declared.

Corresponding author and address for reprints: Andrej Doma, MD, Department of Nuclear Medicine, Institute of Oncology Ljubljana, Zaloška 2, 1000 Ljubljana, Slovenia. E-mail: adoma@onko-i.si.

Online date: April 15, 2019

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